BRS/RA Integrated Conference Programme 2006




THURSDAY 4th MAY 2006

7.30

REGISTRATION
7.45-8.25

RENAL ASSOCIATION ANNUAL GENERAL MEETING

Queens Suite 1

8.30-10.30

Main Auditorium

PLENARY 2: BONE DISEASE
Sponsored by Shire
Co-Chair:  Louise Wells, York Hospital & David Goldsmith, Guy’s Hospital, London
Initiators, Inhibitors and Vesicles in Arterial Calcification.
Catherine Shanahan, BHF Senior Fellow, Addenbrooke’s Hospital, Cambridge
Protecting the dialysis patients from vascular calcification. Geoffrey Block, Director of Clinical Research, Denver Nephrologists, PC, Denver ,USA
Clinical aspects of managing vascular calcification. Mhairi Sigrist, Renal Research Dietitian, Derby City General Hospital
Bone disease and vascular calcification following renal transplantation. John Cunningham, Professor of Nephrology, University College London
10.30-11.00 COFFEE & EXHIBITION - Hall Q

POSTERS - Hall D

11.00-12.15

Main Auditorium

Queens Suite 1

Queens Suite 2

Kings Suite

Conference Room

CKD AS A COMMUNITY DISEASE.
Sponsored by Roche
Chair:Paul Stevens, Kent & Canterbury Hospital

Early detection and prevention: community based cornerstones of modern CKD management.
Guest Speaker: Adeera Levin, Professor of Medicine, University of British Columbia, Canada

O41 Chronic kidney disease in primary care
P K Mitra, St. James Medical Practice, Kings Lynn

CKD in primary care.
Guest Speaker: Ian Wilkinson, General Practitioner, Oldham Primary Care Trust, Manchester
 

THE RENAL REGISTRY
Chair: John Feehally, Leicester General Hospital, President, The Renal Association

The Renal Association UK Renal Registry - A Tool to help improve renal care.
Terry Feest, Professor of Nephrology, Southmead Hospital, Bristol

O42 Does transplantation improve survival for end stage renal disease patients in the UK?
C Dudley, UK Renal Registry, Southmead Hospital, Bristol

O43 Elderly patients on renal replacement therapy in the UK : UK Renal Registry
C Byrne, UK Renal Registry, Southmead Hospital, Bristol

044 Does 1st year renal transplant function influence longer term haemoglobin, bone metabolism and blood pressure ?
R Rao, The Renal Registry, Southmead Hospital, Bristol

CONSERVATIVE CARE FOR PAIENTS WITH End STAGE RENAL FAILURE
Chair: Cathy Holman, York Hospital

O45 Interface of renal and palliative care services: impact of action learning sets?
S Gomm, Hope Hospital, Salford

O46 Effective delivery of a conservative management service for patients with stage 5 CKD
JC Daniels, Kent & Canterbury Hospital

O47 Dialysis or not? A comparative survival study of elderly patients with end stage renal disease
FEM Murtagh, King’s College London

O48 A review of patients receiving conservative care for ESRF
M Higginbotham, York Hospital

O49 Factors influencing the success of running a maximum conservative medical treatment in patients approaching end stage CKD
CF Wong, Royal Liverpool University Hospital

LABORATORY SCIENCE:
PROGRESSION IN RENAL DISEASE.

Chair: Caroline Savage, The Medical School, University of Birmingham

Cell Signalling and new therapies in progressive renal disease.
Guest Speaker: Bruce Hendry, Professor of Renal Medicine, King’s College Hospital, London

O50 Knockout of transglutaminase type 2 slows the development of kidney scarring in the mouse UUO model
NB Mohammed, Sheffield Kidney Institute

O51 Cyclin I protects podocytes from apoptosis by stabilising p21Cip1/Waf1
SV Griffin, University of Washington Medical School, Seattle, WA, USA

O52 Hic-5 Mediates extracellular matrix control of mesangial cell apoptosis
JN Hornigold, St. James’s University Hospital, Leeds

PERITONEAL DIALYSIS FORUM
Co-Chair: Althea Mahon, St. Bartholomew’s and The London Hospital & Nick Topley, Institute of Nephrology, University of Wales College of Medicine

O53 CCL-18 and Angiogenin: Novel cytokines present in PD fluid and involved in regulation of inflammation and fibrosis in the peritoneal membrane
A Ahmad, Imperial College London

O54 CAPD with hypertonic glucose containing solution induces hyperglycaemia and is associated with an adverse haemodynamic response in non-diabetic PD patients
NM Selby, Derby City Hospital

O55 Prediction and consequences of plasma concentrations of Icodextrin (ICO) metabolites in PD patients
SJ Davies, University Hosp. Of North Staffordshire

O56 A retrospective review of peritoneal dialysis and the treatment of severe heart failure
E Green, York Hospital

O57 Clinical risk factors for encapsulating peritoneal sclerosis and the value of abdominal computed tomography as a screening tool
M Chanayireh, Manchester Royal Infirmary

12.15-13.45 LUNCH & EXHIBITION - Hall Q

MODERATED POSTER SESSION 12.45-13.45 - Hall D

13.45-15.15

Main Auditorium

Queens Suite 1

PLENARY 3: END OF LIFE CARE
Co-Chair: Maria Da Silva Gane, Lister Hospital, Stevenage & Aine Burns, Royal Free Hospital, London

Withholding and withdrawing dialysis in terminal renal failure - can it be morally justified?
Guest Speaker:  Dr Raanan Gillon, Professor of Medical Ethics, Imperial College, London

Promoting Excellence in Care of the Dying. Guest Speaker: John Ellershaw, Professor, Director Marie Curie Palliative Care Institute Liverpool, University of Liverpool

Care of the dying - what have we learnt in renal failure?
Guest Speaker: Miss Cath Byrne, Supportive & Palliative Care Education Facilitator, Hope Hospital, Manchester

LABORATORY SCIENCE: RENAL DEVELOPMENT
Chair: Neil Turner, MRC Centre for Inflammation, Edinburgh

New insights into human renal development

Guest Speaker: Paul Winyard, Senior Lecturer in Nephro-Urology, Institute of Child Health, London

O58 Nephrocystin-6, a novel centrosomal protein, is mutated in nephronophthisis with retinal degeneration and cerebellar vermis aplasia, and interacts with ATF4/CREB2
JA Sayer, Institute of Human Genetics International Centre for Life, Newcastle

O59 Developing priming in the neonatal response to renal injury
M Riordan, Yale University School of Medicine, New Haven, USA

O60 A complex containing polycystin-1 and receptor protein tyrosine phosphatases identifies a key phosphotyrosine residue involved in AP-1 signalling
K Thurston, Addenbrooke’s Hospital, Cambridge

O61 Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localisation of polycystin-2 in vivo and in vitro
AJ Streets, Sheffield Kidney Institute

15.15-15.45 COFFEE  & EXHIBITION - Hall Q

POSTERS - HallD

15.45-17.15

Main Auditorium

Queens Suite 1

Queens Suite 2

Kings Suite

MODERNISHING: NEW WAYS OF WORKING
Chair: Donal O’Donoghue, Hope Hospital, Salford

O62 Multidisciplinary training in tunnelled line placement developed by nurses
D Waterhouse, Manchester Royal Infirmary

O63 Including Patient Transport in a Commercial Satellite Dialysis Unit Contract - a way forward?
LC Barker, Royal Berkshire Hospital, Reading

O64 The Champions' Challenge
A Hurley, SW Thames Renal and Transplantation Unit, Carshalton

O65 Are primary care based Renal Disease Management (RDM) programmes the solution to managing the large numbers of patients identified by eGFR reporting?
ML Eddisford, Optimal Renal Care UK Ltd, Lincoln

O66 Strategies to Increase Pre-emptive Living Donor Transplantation
L Burnapp, Kidney Disease Modernisation Initiative, Lambeth and Southwark, London

O67 The Impact of a Low Intensity Programme of Information and Guidance for the Detection and Management of CKD in Primary Care
NJ McIntyre, Nottingham City Hospital

HAEMODIALYSIS FORUM
Co-Chair: Roger Greenwood, Lister Renal Unit, Stevenage & Elizabeth Lindley, St. James’s University Hospital, Leeds

O68 Reduction of dialysate sodium concentration using conventional HD or prescribed end plasma conductivity (Diacontrol®)
NM Selby, Derby City Hospital

O69 The Effect of a Protocol-Based Reduction in Dialysate Calcium to 1.25 mmol/l on Population Outcome and Phosphate Binder Usage
L Wells, York Hospital

O70 Calcific Uraemic Arteriolopathy Causing Skin Necrosis: The UK National Epidemiological Survey
J Hegarty, Hope Hospital, Salford

O71 Long-term Outcomes of On-line Haemodiafiltration
SM Chandna, Lister Hospital, Stevenage

O72 Antibiotic locking for tunneled venous catheters – a single centre, one-year experience
R Fluck, Derby City General Hospital

O73 Starting and Withdrawing Haemodialysis: Associations between Nephrologists’ Opinions, Patient Characteristics, and Practice Patterns (Data from the Dialysis Outcomes and Practice Patterns Study)
H Rayner, Heart of England NHS Foundation Trust, Birmingham

OSMAN LECTURE.
Chair: John Feehally, Leicester General Hospital, President, The Renal Association

Understanding FSGS from the cell to the clinic.
Guest Speaker: Peter Mathieson, Professor of Renal Medicine, Southmead Hospital, Bristol
 
BRS RESEARCH FORUM
Chair: Ken Farrington, Lister Renal Unit, Stevenage

BRS Grant Recipient Presentations

Prognostic significance of serum cystain C: a novel marker of adequacy in patients with end-stage renal failure treated by peritoneal dialysis – A pilot study
E Lamb, Kent & Canterbury Hospital

Evaluation of ANP and BNP kinetics during high flux dialysis
M Suresh, Lister Hospital, Stevenage

Physical capacity and community support needs of haemodialysis patients
P Naish, North Staffordshire Hospital,

Effect of sodium profiling during haemodiafiltration
P McLaren, Lister Hospital, Stevenage

Quality of life in Elderly People on Dialysis
D Lamping, London School of Hygiene and Tropical Medicine

17.25-18.25

Main Auditorium

50 YEARS OF DIALYSIS IN THE UK.
Chair: Aleck Brownjohn (Leeds, UK)
A Clinical and historical perspective. Guest Speaker: Stewart Cameron, Emeritus Professor of Renal Medicine, Melmerby, Cumbria
A Technical perspective. Guest Speaker: Nick Hoenich, Clinical Scientist, University of Newcastle
19.45 BRS/RA RECEPTION AND GALA DINNER AT MAJESTIC HOTEL