BRS/RA Integrated Conference
Friday 16th May 2008: How do we make it better? Improving RRT

 Tuesday 13th May

 Wednesday 14th May

  Thursday 15th May

  Friday 16th May

8.00 REGISTRATION AND COFFEE  

9.00-10.00

Lomond Auditorium

MAKING RENAL REPLACEMENT THERAPY BETTER

Chair: Lisa Burnapp & Donal O’Donoghue

Peritoneal Dialysis
Invited Speaker: Simon Davies, Consultant Renal Physician, University Hospital of Staffordshire

Haemodialysis
Invited Speaker: Roger Greenwood, Consultant Nephrologist, Lister Hospital, Stevenage

Transplantation
Invited speaker: John Forsythe, Consultant Surgeon & Clinical Director, Transplant Unit, Edinburgh Royal Infirmary

Carron

GENETICS AND RENAL DEVELOPMENT
(Renal Science)
Chair: Jamie Davies & David Kavanagh

Uroplakins – Key players in renal development
Invited speaker: Adrian Woolf, Professor, Institute of Child Health, London

O62 Investigating the pathway from mutant complement factor H to Endothelial Injury in Haemolytic Uraemic Syndrome
Dr Sally Johnson, Clinical Research Fellow, University of Birmingham

O63 Investigation of Coronary Artery Disease risk alleles for association with Diabetic Nephropathy
Dr Amy Jane Knight, Lecturer in Bioinformatics, Queens University, Belfast

10.00-10.30 COFFEE & EXHIBITION POSTERS
 
Lomond Auditorium
Alsh
Boisdale
Carron
Dochart

10.30- 12.00

PRESENTATION FROM THE AEG RAINE AWARD WINNER
Chair: John Feehally & Peter Mathieson

Finding genes for diabetic kidney disease: Back to the future
Invited Speaker: Brian Conway, MRC Clinician Scientist, Centre for Inflammation Research in Edinburgh University

O64 Symptom trajectories in conservatively-managed CKD – understanding the impact of symptoms over time
Fliss Murtagh, Research Training Fellow, Kings College London

O65 Predicting Encapsulating Peritoneal Sclerosis: can this be improved by CT scanning and measurement of dialysate cytokines?
Sohail Ahmad, Renal Research Registrar, Hammersmith Hospital

O66 Truncations in the Carboxyl terminus of Human DNA 3’ 5’ Exonuclease TREX1 Cause Autosomal Dominant Retinal Vasculopathy with Cerebral Leukodystrophy
David Kavanagh, University of Newcastle

O67 Macrophages expressing hemoxygenase-1 protect from renal ischaemia-reperfusion injury
David Ferenbach, Clinical Training Fellow, University of Edinburgh

NON MEDICAL LED CARE
Chair: Anne Petherick & Elizabeth Lamerton

O68 Art during HD treatment improves patients’ mental health and sense of wellbeing
Y Mun Woo, Associate Specialist, Inverclyde Royal Hospital

Non medical prescribing
Invited Speaker: Rania Betmouni,
Renal Pharmacist, Hammersmith Hospital

O69 Successful Management of Anaemia in HD Patients by a Pharmacist Prescriber
Maire McManus, Renal Pharmacist, Antrim Area Hospital, N. Ireland

Innovation and practice in the management of renal bone disease
Invited Speaker: Nicki Ruddock, Renal Dietitian Leicester General Hospital

070 Dietetic management of phosphate binder therapy in HD patients: Impact on binder elemental calcium load and costs
Mairi Murray, Renal Dietician, Freeman Hospital, Newcastle

YOUNG PEOPLE ON RENAL REPLACEMENT THERAPY
Chair: Paul Stevens, President British Renal Society & Heather Maxwell

Psychology of Transition
Invited Speaker: Sue Dolby, Consultant Clinical Psychologist, Bristol Children’s Hospital

O71 Action Learning Set on Transition of Adolescent Renal Transplant Recipients
Stephen Marks, Consultant Paediatric Nephrologist, Great Ormond Street Hospital for Children

Invited Speaker: Paul Harden,
Consultant Nephrologist, Churchill Hospital, Oxford

O72 Circulating calcification inhibitors, Fetuin-A and Osteoprotegerin, are associated with vascular stiffness and calcification in children on dialysis
Rukshana Shroff, Research Registrar, Great Ormond Street Hospital for Children

CPD Session: Dialysis
Chair: Rob McTier & Alison Brown

What four steps should be taken to improve mortality rates of haemodialysis patients in the UK
Invited speaker: RN Foley, Associate Professor of Medicine, Memorial University, Minneapolis, U.S.A.

What needs to be done to improve patient safety on haemodialysis?
Invited speaker: Paul Rylance, Consultant Nephrologist, New Cross Hospital, Wolverhampton

Are clinical outcomes better with haemodiafiltration or high flux haemodialysis?
Invited speaker: Ken Farrington, Consultant Nephrologist, Lister Hospital, Stevenag

CLINICAL NEPHROLOGY
Chair: Charles Pusey & Neil Sheerin

O73 Rituximab based on cyclophosphamide-sparing induction therapy in ANCA-associated vasculitis with glomerulonephritis
Alan Salama, Senior Lecturer and Honarary Consultant , UCL Medical School, London

O74 Hereditary renal amyloidosis associated with mutant fibrogen Aa-chain: clinical presentation, molecular basis, histological features and outcome of RRT
Julian Gillmore, Senior Lecturer & Honorary Consultant Nephrologist, UCL Medical School, London

O75 Clinical characteristics and histological findings in liver transplant recipients who have undergone renal biopsy
Aisling O’Riordan, Clinical Research Registrar, Kings College Hospital

O76 Clinical and immunological effects of Infliximab as additional therapy for anti-neutrophil cytoplasm antibody associated vasculitis
Matthew Morgan, Clinical Lecturer in Renal Medicine, University of Birmingham

O77 Clinical characteristics of 13 Greek-Cypriot families with three heterozygous mutations in the COL4A3/COL4A4 genes, showing famial microscopic hematuria, thin glomerular basement membrane nephropathy and late progression to chronic or end-stage renal failure with focal segmental glomerulosclerosis
Alkis Pierides, Nephrologist, Ippokrateon Hospital, Cyprus

12.00-13.30 LUNCH & EXHIBITION                                                                             MODERATED POSTER SESSION

13.30-15.00

         Lomond Auditorium

WHAT MATTERS TO PATIENTS?
Chairs: Jane MacDonald & Bev Matthews

From a patient’s perspective
Invited speaker: Fiona Loud, Chair of the Kidney Alliance

How to ensure you deliver what matters to patients
Invited Speaker: Jonathan Hope, Patient and Chairman of The Kidney Disease Modernisation Initiative, Guy's & St. Thomas' Charity

Supporting patient decision making
Invited Speaker: Simon Watson, Fellow & Hon Consultant Nephrologist, NHS Institute for Innovation & Improvement

Training patients appropriately to support other patients
Invited Speaker: Lisa Silas, Matron, Guy’s & St Thomas’ NHS Trust, London

Panel discussion: to include above plus:
Ray Mackey, NKF Chair
Stephen D’Souza, Consultant Radiologist , Royal Preston Hospital

                                 Alsh

VASCULAR ACCESS
Chairs: Martin Taal & Alison Cornall

Complex access surgery
Invited Speaker: Professor Homer-Vanniasinkam, Leeds

O78 A Survival Analysis of 1200 Vascular Access Procedures
Eric Vilar, Specialist Registrar, Lister Hospital

079 Buttonhole Needling Of Arteriovenous Fistulas: A Randomised Controlled Trial
Stewart Lambie, Consultant Nephrologist, Raigmore Hospital

O80 Comparison of cutting balloon angioplasty versus conventional balloon angioplasty as the primary treatment of HD access stenosis
Kwok-Yi Chung, Visiting Research Fellow, Derby City General Hospital

O81 Risk factors for Catheter Thrombosis: results of a 2 year prospective study
Peter Thomson, Specialist Registrar, Western Infirmary, Glasgow

O82 Successful use of ionic dialysance based vascular access flow as part of a HD surveillance programme
Kwok-Yi Chung, Visiting Research Fellow, Derby City General Hospital

                          Boisdale

DGH nephrology group sponsored session:

MAKING RENAL UNITS SAFER FOR PATIENTS
Chair: Peter Andrews & Paul Rylance

What puts renal patients at risk?
Invited Speaker: Dr Paul Rylance: Consultant Nephrologist, New Cross Hospital, Wolverhampton

Achieving patient safety and improvement
Invited Speaker: Jason Leitch, National Clinical Lead for Safety and Improvement, Scottish Government

A renal nurse perpective of patient safety
Invited Speaker: Anne Petherick, Education Coordinator, Dept Renal Medicine, NHS Lothian

“Getting the boring stuff right”
Invited Speaker:Jasmeet Soar, Safer patients Lead and Clinical Lead for ICU, Southmead Hospital, Bristol

                            Carron

ANIMAL MODELS – WHAT CAN THEY TELL US? (Renal Science)
Chair: Tim Johnson & David Kluth

Immunological glomerulonephritis
Invited Speaker: John Reynolds, Non Clinical Scientist, Imperial College London

Tubulointerstitial models
Invited Speaker: John Haylor, Senior Lecturer, Sheffield Kidney Institute

Experimental peritonitis
Invited Speaker: Nick Topley, Professor of Molecular Biology, Institute of Nephrology, University of Cardiff

What is the relevance of animal models to human disease
Invited Speaker: Terence Cook, Professor of Renal Pathology, Imperial College London

15.00-15.30 COFFEE BREAK
15:30 - 17:00
                                              Alsh
TRANSPLANTATION 2
Chairs: Sue Moore

O83 Withdrawal of all Immunosuppressive Therapy Except Corticosteroid in Renal Transplant Recipients Who Experience Life-Threatening malignancy
Meetali Kolhatkar, FTSTA3, Western Infirmary, Glasgow

O84 Is there a place for beneficial matching of complement C3 allo types in the improvement of long term renal graft outcome
Magdi Yaqoob, Professor of Nephrology, Royal London Hospital


O85 Dissociation between degree of renal impairment and severity of hyperparathyroidism in late post-transplant patients
Elaine Jolly, Specialist registrar, Lister Hospital, Stevenage

O86 Complement activation in antibody incompatible renal transplantation
Rizwan Hamer, Research Registrar, University Hospitals Coventry & Warwickshire

O87 Early to Medium Graft Survival is Excellent in Antibody Incompatible Transplantation, but Mortality is Increased in Association
Rob Higgins, Consultant Nephrologists, University Hospital Coventry

O88 Steroid sparing in ABO incompatible renal transplantation
Jack Galliford, Clinical Research Fellow, Hammersmith Hospital

                                            Boisdale
HOT TOPICS IN CLINICAL NEPHROLOGY
Chairs: Mark MacGregor

O89 Safe MR imaging in atheromatous renovascular disease in the light of nephrogenic systemic fibrosis (NSF)
Christina Chrysochou, Renal Research Fellow, Salford Royal Hospitals NHS Foundation Trust

O90 Management of anaemia in HD patients: do we meet the targets or do we exceed them?
Emmanouil Mazonakis, Senior House Officer in Nephrology, Glasgow Royal Infirmary

O91 Serum Phosphate: Prognostic associations in patients with CKD not on dialysis
Helen Eddington, Renal Research Registrar, Salford Royal Hospitals NHS Foundation Trust

O92 Successful treatment of anti-erythropoietin antibody-mediated pure cell aplasia with hematide, a novel, synthetic, peptide-based erythropoietin receptor agonist
Iain Macdougall, Consultant Nephrologist, Kings College Hospital, London

O93 Discharging patients from the renal clinic to primary care – will they get appropriate monitoring of renal function?
Kate Stevens, Specialty Registrar in Acute Medicine, Inverclyde Royal Hospital

094 Relative risk of death in UK HD patients in relation to achieved haemoglobin from 1999 to 2005: data from the UK Renal Registry
Iain Macdougall, Consultant Nephrologist, Kings College Hospital, London

                                         Carron
RENAL SCIENCE
Chair: Neil Sheerin & Ceri Fielding

095 High glucose causes dysfunction of the glomerular endothelial glycocalyx
Anurag Singh, Clinical Research Fellow, Southmead Hospital, Bristol

096 Multi-photon imaging of live rat kidney slices reveals differences in mitochrondial function between proximal and distal segments of the nephron in response to anoxia
Andrew Hall, Clinical Research Fellow, University College London

097 Syk inhibitor is effective in treatment of established experimental glomerulonephritis
Jennifer Smith, Chief Biomedical Scientist, Imperial College

098 Mesangial cell mannose receptor plays a critical role in the development of crescentic glomerulonephritis
Konstantia-Maria Chavele, PHD Student, Imperial College

099 Subset-specific microRNA expression patterns in effector CD4+ T-cells and the functional effects of the microRNAs miR-142 and mir-181
Karem Atalar, Clinical Research Training Fellow, Guy’s Hospital, London

O100 Apoptotic cell phagocytosis promotes emigration of resident peritoneal macrophages and dendritic cells to lymph nodes
Jeremy Hughes, Reader in Nephrology, Queens Medical Research Institute, University of Edinburgh

17.00 MEETING CLOSES