BRS - British Renal Society

Goals of Session
- Increase awareness of the many achievements and opportunities for international work for UK nephrology especially through partnership with ISN. Increase awareness of the remarkable work of ISN Disaster Relief Task Force at earthquakes and other natural disasters around the world. Promote ISN membership among RA members.
International Society of Nephrology Past, Present and Future
John Feehally - ISN President Elect
UK Contributions to Global Nephrology
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Impact of an ISN Fellowship
Charlotte Osafo - Accra, Ghana
Impact of ISN Sister Renal Centers, Paul Harden, Chair ISN Sister Center Programme, introducing, Cardiff - Nanjing
DongDong Lou - Nanjing, China Abstract
Impact of ISN Sister Centers Oxford - Minsk
Aleh Kalachyk - Minsk, Belarus Abstract
ISN Renal Disaster Relief Task Force - Haiti and so much more
Raymond Vanholder - Professor and Clinical Head of Nephrology, University Hospital Ghent, Belgium Abstract
Discussion: ISN Renal Disaster Task Force - Haiti and so much more
Peter Stockman - Bio- Engineer AZ Groeninge, Kortrijk, Belgium

End of life care in advanced kidney disease - Use of Care Pathways and renal guidelines
Stephanie Gomm - Consultant in Palliative Medicine, Salford Royal NHS Foundation Trust
Primary Care Perspective of Renal Palliative Care
David Mazza - GP, York
O9 Does regular palliative care consultation improve symptom burden in patients with advanced chronic kidney disease (CKD) attending a renal conservative management service?
Fiona McFatter - SpR, NHS Tayside Abstract
O10 Attitudes and perceptions of patients, family and staff to end of life care planning in dialysis
Maria SaSilva Gane - Counsellor, Lister Hospital, Stevenage Abstract

Does interdisciplinary science have a role in kidney research?
John Mullins - Professor and Wellcome Trust Principal Research Fellow, Molecular Physiology, University of Edinburgh
O11 Transforming Growth Factor-β1 Represses Transcription of MicroRNA-192 and Promotes Fibrosis in Chronic Kidney Disease
Robert Jenkins - Research Scientist, Institute of Nephrology, Cardiff University Abstract
O12 Macrophages regulate pressor responses to endothelin-1
Elizabeth Owen - Research Fellow, University of Edinburgh Abstract
O13 A novel role for CD2AP in normal podocyte differentiation
Ramadan Sarrab - Medical Student, Southmead Hospital, Bristol Abstract
O14 Embryonic stem cell-derived macrophages - a novel approach to developing anti-inflammatory macrophages for cell therapy
Noemie Nkejabega - PhD Student, University of Edinburgh Abstract

Growth in the number of patients on RRT - insights from the UK Renal Registry
Charlie Tomson - Consultant Nephrologist, Southmead Hospital, Bristol
O15 The change to HRG 4 has a major impact on income in Nephrology despite robust Consultant led clinical audit of coding data
Darren Parsons - Consultant Nephrologist, Imperial College Healthcare NHS Trust Abstract
O16 Reducing expenditure on locum nursing staff by 60% over 3 months on a Nephrology ward, using a Quality Improvement Approach
Jane Macdonald - Lead Nurse, Salford Royal NHS Foundation Trust Abstract
Increasing numbers of patients, decreasing income: the perfect storm
Ruth Hussey - Regional Director of Public Health, NHS North West

10:30 - 11:00 - Coffee & Exhibition

11:00 - 12:30 -

Auditorium

Charter Suite 3 - 5

Central Meeting Rooms 5, 6 & 7

Charter A

Smoothing Pathways in Renal Replacement Therapy

Presentation from the AEG Raine Award Winner

Dealing with Virus in Renal Treatment

CKD Forum Session 2: Quality Initiatives in CKD **

Chair: Martin Wilkie and Sue Cox

Chair: Peter Mathieson

Chair: Bruce Hendry and Lisa Burnapp

Chair: Stephen Morgan and Ian Wilkinson

Ensuring equality of access to peritoneal dialysis for patients undergoing an unplanned start to RRT
Jan Povlsen - Consultant Nephrologist, Associate Professor Aarhus University Hospital, Denmark
O17 Late referral to Nephrology services: What effect on quality of life?
Vikas Lodhi - SpR, University Hospital of Wales Abstract
O18 ‘Acute’ Peritoneal Dialysis Experience: Immediate-Start Peritoneal Dialysis is a Safe and Feasible Option
Kate Wiles - Renal SpR, Wessex Renal and Transplantation Unit, Portsmouth Abstract
O19 Chronic Renal Insufficiency Standards Implementation Study (CRISIS): Predictors of rapid progression of chronic kidney disease in a referred cohort
Richard Hoefield - Clinical Research Fellow, Salford Royal NHS Foundation Trust Abstract
O20 Late presentation of patients with ESRD for renal replacement therapy is avoidable in the minority
Udaya Udayaraj - Consultant Neprologist, Southmead Hospital, Bristol Abstract

Regulation of glomerular permeability
Andrew Salmon - Lecturer in Nephrology & Honorary Research Fellow in Physiology, Richard Bright Renal Unit, Southmead Hospital, Bristol
O21 Novel genetic cause of renal tubulopathy, mutations in KCNJ10 cause EAST syndrome (Epilepsy, Sensorineural deafness and Tubulopathy) and lead to new insights into renal tubular mechanisms
Sally Feather - Consultant, St James's University Hospital, Leeds Abstract
O22 Multiphoton imaging of mitochondrial function in the isolated perfused rat kidney
Andrew Hall - Clinical Lecturer, Centre for Nephrology, University College London Abstract
O23 Randomised Controlled Trial of Mycophenolate Mofetil versus Azathioprine for Maintenance Therapy in ANCA-Associated Vasculitis (IMPROVE)
Thomas Hiemstra - Research Fellow and Honorary SpR, Department of Medical Genetics, Cambridge Institute for Medical Research Abstract
O24 Renal disease is associated with accelerated vascular ageing
Laurie Tomlinson - Clinical Lecturer, Vascular Research Centre, Addenbrooke's Hospital, Cambridge Abstract

HIV nephropathies and haemodialysis
Trevor Gerntholtz - Nephrologist, Director of Research, Chris Hani Baragwanath Hospital, Johannesburg, South Africa
Viral impact in transplantation
Chas Newstead - Consultant Renal Physician, St James’s University Hospital, Leeds

QICKD study epidemiology update
Kevin Harris - Consultant Nephrologist, University Hospitals of Leicester NHS Trust
Care Bundle – How does it work in primary care? Developing and writing Care Bundle for CKD
Simon Watson - Consultant Nephrologist, Royal Infirmary of Edinburgh
Care Bundle - How does it work in primary care? Implementing and evaluating the CKD Bundle in general practice
Nicola Thomas - Senior Lecturer in Renal Care, School of Community and Health Sciences, City University, London
O25 What is the impact of Renal Indicators in the Quality and Outcomes Framework on the control of blood pressure in people with chronic Kidney disease stage 3-5?
Kushan Karunaratne - Medical Student, Kent Kidney Care Centre, East Kent Hospitals University NHS Foundation Trust Abstract
O26 Minimising the gap between Expected and Recorded Prevalance of Chronic Kidney Disease (CKD) in Primary Care
Maciej Gwozdziewicz - Knowledge Transfer Associate, Salford Royal NHS Foundation Trust Abstract

** This session has been sponsored by the DGH Nephrologists

12:30 - 13:30 - Moderated Poster Session 2 & Coffee

13:30 - 14:30 - Lunch & Exhibition

14:30 - 16:00 -

Auditorium

Charter Suite 3 - 5

Osman Lecture

CKD Forum Session
Interactive CKD Workshop

Chair: Caroline Savage

Chair: Ian John and Karen Jenkins

The antigenic target in membranous nephropathy
David Salant - Professor of Medicine, Chief, Renal Section, Boston University Medical Center, Boston University School of Medicine, Massachusetts, USA
O27 IFN-γ and STAT1 regulate the MMP:TIMP balance during the development of inflammation-induced peritoneal fibrosis
Ceri Fielding - Research Fellow, Cardiff University Abstract
O28 A CD8 T cell transcription signature predicts prognosis in autoimmune disease
Eoin McKinney - Clinical Research Fellow, Addenbrooke's Hospital, Cambridge Abstract
O29 Conditioning the Uraemic Heart
Kieran McCafferty - Clinical Research Fellow, Queen Mary University London Abstract

CKD in Primary Care - Challenges & Solutions
Paula D'Souza - Renal Specialist Nurse, Exeter Primary Care Trust Abstract
Management of CKD: in the older person
Robert Lewis - Consultant Nephrologist, Wessex Regional and Transplant Unit, Portsmouth Digivote discussion Abstract
Management of CKD: in heart failure
Kathryn Griffith - GP, Dr Price & Partners, University Health Centre, York University Digivote discussion

16:00 - 16:30 - Coffee & Exhibition

16:30 - 18:00 -

Auditorium

Charter Suite 3 - 5

Central Meeting Room 5, 6 & 7

Central Meeting Room 3 & 4

Charter A

Diabetes Science and Clinical

Hypertension and Tubule

Glomerular Disease

Renal Replacement Therapy

BRS Research Forum

Chair: Damian Fogarty and Kathryn Griffith

Chair: Robert Unwin

Chair: Alan Salama

Chair: Chris McIntyre

Chair: Simon Ball

O30 Modest reduction in salt intake lowers blood pressure and urinary albumin excretion in individuals with impaired glucose tolerance and type 2 diabetes
Rebecca Suckling - SpR, St Georges University of London Abstract
New & emergent therapies for diabetes
Invited Speaker tbc -
O31 Specific loss of insulin signalling to the kidney podocyte recapitulates features of diabetic nephropathy
Richard Coward - Clinician Scientist, Academic Renal Unit, Southmead Hospital, Bristol Abstract
Diabetes and the kidney where are we now?
Eberhard Ritz - Professor, Chief of the Division of Nephrology, University of Heidelberg, Germany Abstract

Genomics, proteomics, and other omics in Cardiovascular medicine
Anna Dominiczak - British Heart Foundation Professor of Cardiovascular Medicine, University of Glasgow Abstract
O32 Left Atrial Volume is associated with Haemodialysis-Induced Ischaemic Cardiac Injury (Myocardial Stunning) and Reduced Survival
Helen Jefferies - Research Registrar, Royal Derby Hospital Abstract
O33 Blood pressure and mortality in haemodialysis (HD) patients from DOPPS
Richard Fluck - Consultant Nephrologist, Royal Derby Hospital Abstract
O34 Antihypertensive therapy is associated with sustained improvement in cardiovascular function whilst body composition deteriorates in older people with chronic kidney disease
Stephen John - Research Registrar, Royal Derby Hospital Abstract
O35 Rapid changes in plasma sodium concentration influence blood pressure in individuals on haemodialysis
Rebecca Suckling - SpR, St Georges University of London Abstract

New Therapies for Vasculitis – Rituximab: where and when to use
David Jayne - Consultant in Nephrology and Vasculitis, Addenbrookes Hospital, Cambridge
O36 Deletion of inhibitory Fc gamma receptor 2B (CD32B) on myeloid cells rather than B cells enhances murine immune complex glomerulonephritis
Ruth Tarzi - Senior Lecturer, Imperial College London Abstract
O37 Glomerular macrophage expression of calprotectin and circulating calprotectin levels are increased in patients with ANCA associated vasculitis and promote glomerulonephritis
Ruth Pepper - Clinical Research Fellow, Imperial College Kidney and Transplant Institute, London Abstract
O38 Abnormal O-glycosylation of serum IgA1 early in the disease is associated with risk of progression in IgA Nephropathy
Javeria Peracha - Intercalating Medical Student, University of Leicester Abstract
O39 Alveolar Haemorrhage in ANCA associated Vasculitis
Alina Casian - Vasculitis Clinical Research Fellow, Addenbrooke's Hospital, Cambridge, Abstract

What have we learned from BOLDE
Edwina Brown - Professor of Renal Medicine, Imperial College, London
O40 Associations between dialysis unit mean treatment time and patient outcomes:: Data from the DOPPS
Hugh Rayner - Consultant Nephrologist, Birmingham Heartlands Hospital Abstract
O41 A Randomised, Double Blind, Controlled Trial of Taurolidine-Citrate Catheter Locks for the Prevention of Bacteraemia in Patients treated with Haemodialysis
Laurie Solomon - Consultant Nephrologist, Royal Preston Hospital Abstract
O42 Serological markers of bone turnover in a haemodialysis population and their association with parathyroid hormone levels
Kevin Eardley - Consultant Nephrologist, Shrewsbury and Telford Hospitals NHS Trust Abstract
O43 Use of High Magnesium Dialysate does not Abrogate Intradialytic Haemodynamic Instability or Haemodialysis-induced Myocardial Stunning
Helen Jefferies - Research Registrar, Royal Derby Hospital Abstract

Scientific and clinical evaluation of the use of bioimpedence spectroscopy and a 3-compartment model to monitor body composition in paediatric dialysis patients
Elizabeth Lindley - Clinical Scientist in Renal Medicine, St. James’s University Hospital Abstract
What is the scale of non-adherence to blood pressure medication to CKD; its predictors and opportunities for intervention
Chris Jones - Nurse Consultant, Kings College Hospital, London Abstract
Free light removal by high cut-off haemodialysis a novel management strategy for myeloma kidney
Colin Hutchinson - Clinical Lecturer, University Hospital Birmingham
How to improve your grant applications
Donna Lamping - Professor of Psychology, London School of Hygiene & Tropical Medicine

19:30 - - BRS / RA Reception and Gala Dinner

MCC

Drinks and Gala Dinner
Drinks in the Exhibition for 30 minutes, followed by the GALA DINNER at the MCC. Interactive Games and Band: Sounds of the Blues Brothers

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